08:30-10:45 Keynote Speech:

Moderators:

Weidong Le (University of Electronic Science and Technology of China, China)

Hao Qian (University of Electronic Science and Technology of China, China)

Ruxiang Xu (Sichuan Academy of Medical Sciences and Sichuan People's Hospital, China)

08:30-09:00 Recent Advances of Regeneration of Optic nerve in animals

Kwok-fai So (The University of Hong Kong; GHM Institute of CNS Regeneration; Jinan University, China)

09:00-9:30 Mechanism of blindness caused by abnormal lipid metabolism

Zhenglin Yang (Sichuan Academy of Medical Sciences and Sichuan People's Hospital, China)

09:30-10:15 Psychosomatic and Mental Illness are Immune-Mediated Neurotoxicity Disorders

Michael H. J. Maes (University of Electronic Science and Technology of China, China)

10:15-10:45 Discussion

10:45-11:00 Coffee break

11:00-12:30 Session 01: Regenerative Medicine

Moderators:

Jiasong Guo (Southern Medical University, China)

Letao Yang (Tongji University, China)

11:00-11:30 Control mechanisms in CNS and PNS repair and regeneration

Simone Di Giovanni (Imperial College London, UK)

11:30-12:00 In vivo reprogramming for neural regeneration

Chun-Li Zhang (University of Texas Southwestern Medical Center, USA)

12:00-12:30 Discussion

12:30-13:30 Lunch break

13:30-15:30 Session 02: Advanced Technology in Neuroscience

Moderators:

Jing Yang (University of Electronic Science and Technology of China, China)

Lu Yang (University of Electronic Science and Technology of China, China)

13:30-14:00 Engineering human brain organoids for modeling brain development and neural regeneration

Guo-Li Ming (University of Pennsylvania, USA)

14:00-14:30 Molecular landscapes of adult hippocampal neurogenesis from rodents, primates to humans

Hongjun Song (University of Pennsylvania, USA)

14:30-15:00 Human iPSC-based disease modeling and therapeutic development

Yanhong Shi (Beckman Research Institute of City of Hope, USA)

15:00-15:30 Discussion

15:30-15:45 Coffee break

15:45-17:45 Session 03: Aging and Brain Repair

Moderators:

Weidong Le (University of Electronic Science and Technology of China, China)

Chongkui Sun (Sichuan Academy of Medical Sciences and Sichuan People's Hospital, China)

15:45-16:15 Improving ER proteostasis delays brain aging and age-related diseases

Claudio Hetz (University of Chile, Chile)

16:15-16:45 iPSCs from Alzheimer’s disease patients display neuronal differentiation impairment of neural progenitor cells

Weidong Le (University of Electronic Science and Technology of China, China)

16:45-17:15 Lights-on for better brain function: exploring the benefits of photobiomodulation

John Mitrofanis (Université Grenoble Alpes, France)

17:15-17:45 Discussion

18:00-19:30 Banquet Dinner & Open Ceremony

08:30-10:00 Session 04: Brain Injury and Pain Processing

Moderators:

Ziyan Wang (University of Electronic Science and Technology of China, China)

Cheng Yin (Sichuan Academy of Medical Sciences and Sichuan People's Hospital, China)

08:30-09:00 The closed-loop circuit for chronic pain

Xiaoke Chen (Stanford University, USA)

09:00-09:30 The nervous face of the Vascular Endothelial Growth Factor-A: hypersensitivity and neuroprotection

Lorenzo Di Cesare Mannelli (University of Florence, Italy)

09:30-10:00 Discussion

10:00-10:15 Coffee break

10:15-12:15 Session 05: New Drug Development and Treatment of Nervous System Diseases

Moderators:

Ying Shi (University of Electronic Science and Technology of China, China)

Cunjin Zhang (Sichuan Academy of Medical Sciences and Sichuan People's Hospital, China)

10:15-10:45 Neuro-mechanisms underlying the antidepressant effects of physical exercise

Sonata Yau (Hong Kong Polytechnic University, China)

10:45-11:15 Left-right side-specific endocrine signaling from injured brain: challenging neurological dogma

Mengliang Zhang (University of Southern Denmark, Denmark)

11:15-11:45 The mechanism and clinical translation of Th17 cells in multiple sclerosis

Cunjin Zhang (Sichuan Academy of Medical Sciences and Sichuan People's Hospital, China)

11:45-12:15 Discussion

12:15-13:15 Lunch break

13:30-15:00 Session 06: Novel Targets, Treatments, and Avenues for Ischemic Stroke

Moderators:

Yeming Yang (University of Electronic Science and Technology of China, China)

Yi Zheng (University of Electronic Science and Technology of China, China)

13:30-14:00 Targetting ferroptosis for ischemic stroke

Peng Lei (West China Hospital of Sichuan University, China)

14:00-14:30 Clinical translational study of NSC intracerebral precision transplantation for repairing hemiplegia after ischemic brain injury

Ruxiang Xu (Sichuan Academy of Medical Sciences and Sichuan People's Hospital, China)

14:30-15:00 Discussion

15:00-15:15 Coffee break

15:15-17:15 Session 07: Spinal Cord Injury

Moderators:

Jing Hu (University of Electronic Science and Technology of China, China)

Huan Xiong (Sichuan Academy of Medical Sciences and Sichuan People's Hospital, China)

15:15-15:45 Clearance of myelin debris: molecular mechanisms and implications in spinal cord injury

Yi Ren (Florida State University College of Medicine, USA)

15:45-16:15 Promote axon regeneration and functional rewiring in the adult CNS by targeting phosphatases

Kai Liu (The Hong Kong University of Science and Technology, China)

16:15-16:45 Gliotransmission and adenosine signaling promote axon regeneration

Yang Xiang (University of Massachusetts Chan Medical School, USA)

16:45-17:15 Discussion

18:00-19:30 Banquet Dinner & NRR Night

08:30-12:00 Youth Scientists Forum 01 (English)

Order of Presentations: Arranged in alphabetical order by their last name

Session Chair: Kai Liu (The Hong Kong University of Science and Technology, China)

Referees: Simone Di Giovanni, Kai Liu, Guo-Li Ming, Hongjun Song, Ruxiang Xu

Jian'an Chen, Beihang University

Title: An overview of the current spinal cord injury models

Yu Hu, West China Hospital of Sichuan University

Title: 3D printing of functional nerve guide conduits for peripheral nerve regeneration

Chaochao Li, Chinese PLA General Hospital

Title: Tissue engineering nerve grafts repair nerve defects and clinical application

Yuanlong Li, Guangdong Provincial People's Hospital

Title: Enucleated M2 type microglia for MCT1-IN-M3 delivery to treat spinal cord injury

Zhiwei Li, Qilu Hospital of Shandong University

Title: Electrospun 3D spinal cord-mimicking model systems for spinal cord regeneration

Ziyu Li, The Second Hospital of Anhui Medical University

Title: PDGF/PDGFRβ pathway induces fibrotic scar formation after spinal cord injury

Jialin Liu, The Third Affiliated Hospital of Sun Yat-Sen University

Title: The therapeutic mechanism of transcranial iTBS on nerve regeneration and functional recovery in rats with complete spinal cord transection

Xiaoyin Liu, West China Hospital of Sichuan University

Title: Enhanced biomimetic hydrogels stress relaxation ameliorates traumatic brain injury repair by promoting migration and differentiation of endogenous stem cells

Xiang Mao, The First Affiliated Hospital of Anhui Medical University

Title: Chronic histopathological and functional outcome after controlled cortical impact trauma in mice

Wenrui Qu, The Second Norman Bethune Hospital of Jilin University

Title: Schwann cell migration-mediated restoration of neural connection and functional recovery following spinal cord injuries

Saijilafu, Hangzhou City University

Title: GDNF- loaded polydopamine scaffolds promote spinal cord repair

Jianhao Wang, Tianjin Medical University General Hospital

Title: The Bionic Spinal Cord Scaffold Promotes Directed Axonal Growth to Repair Spinal Cord Injury

Yanchao Wang, West China Hospital of Sichuan University

Title: Application of Polyurethanes Scaffold in Central Nerve Repair

Yunyun Wang, The General Hospital of Western Theater Command PLA

Title: Valeriana Jatamansi Jones Promotes Axonal Regeneration and Functional Recovery in Spinal Cord Injury via PI3K/Akt Signaling

Wanlin Xu, Shanghai Ninth People's Hospital

Title: Injectable Hydrogel Encapsulating Proangiogenic Factor Facilitates Peripheral Nerve Repair via Re-vascularization and Immunoregulation

Letao Yang, Tongji University

Title: Nanotechnology-enabled Stem Cell Enginering for Spinal Cord   Repair and Neuroregeneration

08:30-12:00 Youth Scientists Forum 02 (English)

Order of Presentations: Arranged in alphabetical order by their last name

Session Chair: Sonata Yau (Hong Kong Polytechnic University, China)

Referees: Lorenzo Di Cesare Mannelli, Claudio Hetz, Peng Lei, Michael H. J. Maes, Yanhong Shi, Sonata Yau, Cunjin Zhang

Tingjun Chen, University of Health and Rehabilitation Sciences

Title: Microglial sex difference in neuromyelitis optica pathogenesis

Xiaoxuan Fan, Affiliated Hospital of Shaanxi University of Chinese Medicine

Title: Kidney-tonifying Chinese medicine can promote the repair of nerve demyelination：An experimental study in demyelinating mouse model

Yuning Feng, Affiliated Hospital of Shaanxi University of Chinese Medicine

Title: Analysis of risk factors related to Intracerebral Hemorrhage

Chong Gao, Hangzhou City University

Title: Developing ALS model with neuromuscular organoids

Haijun Han, Hangzhou City University

Title: Study on FZD6 in depression through hippocampal neurogenesis mediated by Wnt/beta-catenin pathway

Xiaohua Jiang, The Chinese University of Hong Kong

Title: Application of Ectodermal Mesenchymal Stem Cells in Ischemic Brain Damage

Zhanfeng Jiang, General Hospital of Ningxia Medical University

Title: Lycium Barbarum Glycopeptide inhibits neuroinflammation by promoting the secretion of DHA by microglia

Longjie Lin, Affiliated Hospital of Shaanxi University of Chinese Medicine

Title: Research progress on the mechanism of Chinese herbal medicine promoting myelin sheath repair

Chang Liu, Shanghai Jiao Tong University

Title: Stroke-induced Phenotype of Neuroinflammatory Astrocytes Disrupts Blood-Brain Barrier Integrity via Matrix Metalloproteinase-3

Jingjing Liu, Lanzhou University

Title: Fecal microbiome transplantation alleviates manganese-induced neurotoxicity through altering gut microbiota composition and function associated with the cGAS–STING/NLRP3 pathway

Sheng Liu, Zhongshan Ophthalmic Center, Sun Yat-Sen University

Title: The cellular and molecular mechanisms of visual information processing

Yi Wang, Zhejiang Chinese Medical University

Title: Adult-born neurons aggravate epileptic seizures via local aberrant excitatory circuits

Anguo Wu, Southwest Medical University

Title: Targeting autophagy as a therapeutic strategy for the identification of lignans from Peristrophe japonica in Parkinson’s disease

Tongtong Xu, Shanghai Jiao Tong University

Title: Astrocytic MEGF10- and MERTK-mediated myelin phagocytosis differentially affects white matter repair in mice after chronic cerebral hypoperfusion

Qing Zeng, Zhujiang Hospital of Southern Medical University

Title: Supramolecular hybrid hydrogel delivers exosomes derived from IL-1β stimulated BMSCs to attenuate neuroinflammation in cerebral ischemia-reperfusion injury

08:30-12:00 Youth Scientists Forum 03 (English)

Order of Presentations: Arranged in alphabetical order by their last name

Session Chair: Mengliang Zhang (University of Southern Denmark, Denmark)

Referees: Wedong Le, John Mitrofanis, Yi Ren, Yang Xiang, Chun-Li Zhang, Mengliang Zhang

Junhao Deng, Chinese PLA General Hospital

Title: Repopulated microglia promotes tissue repair and functional recovery after spinal cord injury

Yuzhen Dong, The First Affiliated Hospital of Xinxiang Medical University

Title: The study of regenerative for spinal cord injury (SCI)

Lanya Fu, Southern Medical University

Title: miR301a knockout attenuates the Wallerian degeneration and peripheral nerve regeneratin via YY1/CXCR4 patway

Fanqi Meng, Xuanwu Hospital Capital Medical University

Title:

Botao Tan, The Second Affiliated Hospital of Chongqing Medical University

Title: Activity dependent repair after spinal cord injury

Zhifang Xu, Tianjin University of Traditional Chinese Medicine

Title: The   Mechanism of Wake-Promoting Efficacy of Acupuncture at Jing-Well Points for Traumatic Brain Injury-induced Coma via Regulation of vPAG-Lateral Hypothalamic Circuit

Qi Zhan, Tianjin Medical University General Hospital

Title: Natural and bioinspired platform for efficient delivery of RNA therapeutics to the central nervous system

Deteng Zhang, Qingdao University

Title: Bioactive scaffolds enhanced nerve regeneration

Lijian Zhang, Affiliated Hospital of Hebei University

Title: Molecular mechanism of olfactoryensheathing cells regulating neuroinflammation after spinal cord injury

Meng Zhang, Peking University People's Hospital

Title: NGF-loaded bionic adhesive chitosan conduit for sutureless repair of peripheral nerve injury

Yikui Zhang, Eye Hospital of Wenzhou Medical University

Title: Investigating white matter protection strategies via spatial-seq in a large animal model of optic nerve concussion

Meidan Zhao, Tianjin University of Traditional Chinese Medicine

Title: Adiponectin-mediated electroacupuncture improves depression-like behavior in CUMS rats

Meiling Zhou, Jianghan University

Title: Ngn2 and Isl1-mediated astrocyte-to-neuron conversion in vivo promotes functional recovery after spinal cord injury

Mi Zhou, Tianjin Medical University General Hospital

Title: Contact Separation Triboelectric Nanogenerator Based neurostimulation for Effective Sciatic Nerve Restoration

Tian Zhou, Chinese Academy of Sciences

Title: Blood-brain barrier constituents: emerging phagocytic cells in central nervous system