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2023 Joint symposium of International Neural Regeneration Symposium (INRS) 14th Asia Pacific Symposium on Neural Regeneration (APSNR) Annual Meeting of Neural Regeneration and Repair Committee Chengdu, China October 20-22
08:30-22:30 Registration 08:30-10:45 Keynote Speech: Moderators: Weidong Le (University of Electronic Science and Technology of China, China) Hao Qian (University of Electronic Science and Technology of China, China) Ruxiang Xu (Sichuan Academy of Medical Sciences and Sichuan People's Hospital, China) 08:30-09:00 Recent Advances of Regeneration of Optic nerve in animals Kwok-fai So (The University of Hong Kong; GHM Institute of CNS Regeneration; Jinan University, China) 09:00-9:30 Mechanism of blindness caused by abnormal lipid metabolism Zhenglin Yang (Sichuan Academy of Medical Sciences and Sichuan People's Hospital, China) 09:30-10:15 Psychosomatic and Mental Illness are Immune-Mediated Neurotoxicity Disorders Michael H. J. Maes (University of Electronic Science and Technology of China, China) 10:15-10:45 Discussion 10:45-11:00 Coffee break 11:00-12:30 Session 01: Regenerative Medicine Moderators: Jiasong Guo (Southern Medical University, China) Letao Yang (Tongji University, China) 11:00-11:30 Control mechanisms in CNS and PNS repair and regeneration Simone Di Giovanni (Imperial College London, UK) 11:30-12:00 In vivo reprogramming for neural regeneration Chun-Li Zhang (University of Texas Southwestern Medical Center, USA) 12:00-12:30 Discussion 12:30-13:30 Lunch break 13:30-15:30 Session 02: Advanced Technology in Neuroscience Moderators: Jing Yang (University of Electronic Science and Technology of China, China) Lu Yang (University of Electronic Science and Technology of China, China) 13:30-14:00 Engineering human brain organoids for modeling brain development and neural regeneration Guo-Li Ming (University of Pennsylvania, USA) 14:00-14:30 Molecular landscapes of adult hippocampal neurogenesis from rodents, primates to humans Hongjun Song (University of Pennsylvania, USA) 14:30-15:00 Human iPSC-based disease modeling and therapeutic development Yanhong Shi (Beckman Research Institute of City of Hope, USA) 15:00-15:30 Discussion 15:30-15:45 Coffee break 15:45-17:45 Session 03: Aging and Brain Repair Moderators: Weidong Le (University of Electronic Science and Technology of China, China) Chongkui Sun (Sichuan Academy of Medical Sciences and Sichuan People's Hospital, China) 15:45-16:15 Improving ER proteostasis delays brain aging and age-related diseases Claudio Hetz (University of Chile, Chile) 16:15-16:45 iPSCs from Alzheimer’s disease patients display neuronal differentiation impairment of neural progenitor cells Weidong Le (University of Electronic Science and Technology of China, China) 16:45-17:15 Lights-on for better brain function: exploring the benefits of photobiomodulation John Mitrofanis (Université Grenoble Alpes, France) 17:15-17:45 Discussion 18:00-19:30 Banquet Dinner & Open Ceremony 08:30-10:00 Session 04: Brain Injury and Pain Processing Moderators: Ziyan Wang (University of Electronic Science and Technology of China, China) Cheng Yin (Sichuan Academy of Medical Sciences and Sichuan People's Hospital, China) 08:30-09:00 The closed-loop circuit for chronic pain Xiaoke Chen (Stanford University, USA) 09:00-09:30 The nervous face of the Vascular Endothelial Growth Factor-A: hypersensitivity and neuroprotection Lorenzo Di Cesare Mannelli (University of Florence, Italy) 09:30-10:00 Discussion 10:00-10:15 Coffee break 10:15-12:15 Session 05: New Drug Development and Treatment of Nervous System Diseases Moderators: Ying Shi (University of Electronic Science and Technology of China, China) Cunjin Zhang (Sichuan Academy of Medical Sciences and Sichuan People's Hospital, China) 10:15-10:45 Neuro-mechanisms underlying the antidepressant effects of physical exercise Sonata Yau (Hong Kong Polytechnic University, China) 10:45-11:15 Left-right side-specific endocrine signaling from injured brain: challenging neurological dogma Mengliang Zhang (University of Southern Denmark, Denmark) 11:15-11:45 The mechanism and clinical translation of Th17 cells in multiple sclerosis Cunjin Zhang (Sichuan Academy of Medical Sciences and Sichuan People's Hospital, China) 11:45-12:15 Discussion 12:15-13:15 Lunch break 13:30-15:00 Session 06: Novel Targets, Treatments, and Avenues for Ischemic Stroke Moderators: Yeming Yang (University of Electronic Science and Technology of China, China) Yi Zheng (University of Electronic Science and Technology of China, China) 13:30-14:00 Targetting ferroptosis for ischemic stroke Peng Lei (West China Hospital of Sichuan University, China) 14:00-14:30 Clinical translational study of NSC intracerebral precision transplantation for repairing hemiplegia after ischemic brain injury Ruxiang Xu (Sichuan Academy of Medical Sciences and Sichuan People's Hospital, China) 14:30-15:00 Discussion 15:00-15:15 Coffee break 15:15-17:15 Session 07: Spinal Cord Injury Moderators: Jing Hu (University of Electronic Science and Technology of China, China) Huan Xiong (Sichuan Academy of Medical Sciences and Sichuan People's Hospital, China) 15:15-15:45 Clearance of myelin debris: molecular mechanisms and implications in spinal cord injury Yi Ren (Florida State University College of Medicine, USA) 15:45-16:15 Promote axon regeneration and functional rewiring in the adult CNS by targeting phosphatases Kai Liu (The Hong Kong University of Science and Technology, China) 16:15-16:45 Gliotransmission and adenosine signaling promote axon regeneration Yang Xiang (University of Massachusetts Chan Medical School, USA) 16:45-17:15 Discussion 18:00-19:30 Banquet Dinner & NRR Night 08:30-12:00 Youth Scientists Forum 01 (English) Order of Presentations: Arranged in alphabetical order by their last name Session Chair: Kai Liu (The Hong Kong University of Science and Technology, China) Referees: Simone Di Giovanni, Kai Liu, Guo-Li Ming, Hongjun Song, Ruxiang Xu Jian'an Chen, Beihang University Title: An overview of the current spinal cord injury models Yu Hu, West China Hospital of Sichuan University Title: 3D printing of functional nerve guide conduits for peripheral nerve regeneration Chaochao Li, Chinese PLA General Hospital Title: Tissue engineering nerve grafts repair nerve defects and clinical application Yuanlong Li, Guangdong Provincial People's Hospital Title: Enucleated M2 type microglia for MCT1-IN-M3 delivery to treat spinal cord injury Zhiwei Li, Qilu Hospital of Shandong University Title: Electrospun 3D spinal cord-mimicking model systems for spinal cord regeneration Ziyu Li, The Second Hospital of Anhui Medical University Title: PDGF/PDGFRβ pathway induces fibrotic scar formation after spinal cord injury Jialin Liu, The Third Affiliated Hospital of Sun Yat-Sen University Title: The therapeutic mechanism of transcranial iTBS on nerve regeneration and functional recovery in rats with complete spinal cord transection Xiaoyin Liu, West China Hospital of Sichuan University Title: Enhanced biomimetic hydrogels stress relaxation ameliorates traumatic brain injury repair by promoting migration and differentiation of endogenous stem cells Xiang Mao, The First Affiliated Hospital of Anhui Medical University Title: Chronic histopathological and functional outcome after controlled cortical impact trauma in mice Wenrui Qu, The Second Norman Bethune Hospital of Jilin University Title: Schwann cell migration-mediated restoration of neural connection and functional recovery following spinal cord injuries Saijilafu, Hangzhou City University Title: GDNF- loaded polydopamine scaffolds promote spinal cord repair Jianhao Wang, Tianjin Medical University General Hospital Title: The Bionic Spinal Cord Scaffold Promotes Directed Axonal Growth to Repair Spinal Cord Injury Yanchao Wang, West China Hospital of Sichuan University Title: Application of Polyurethanes Scaffold in Central Nerve Repair Yunyun Wang, The General Hospital of Western Theater Command PLA Title: Valeriana Jatamansi Jones Promotes Axonal Regeneration and Functional Recovery in Spinal Cord Injury via PI3K/Akt Signaling Wanlin Xu, Shanghai Ninth People's Hospital Title: Injectable Hydrogel Encapsulating Proangiogenic Factor Facilitates Peripheral Nerve Repair via Re-vascularization and Immunoregulation Letao Yang, Tongji University Title: Nanotechnology-enabled Stem Cell Enginering for Spinal Cord Repair and Neuroregeneration 08:30-12:00 Youth Scientists Forum 02 (English) Order of Presentations: Arranged in alphabetical order by their last name Session Chair: Sonata Yau (Hong Kong Polytechnic University, China) Referees: Lorenzo Di Cesare Mannelli, Claudio Hetz, Peng Lei, Michael H. J. Maes, Yanhong Shi, Sonata Yau, Cunjin Zhang Tingjun Chen, University of Health and Rehabilitation Sciences Title: Microglial sex difference in neuromyelitis optica pathogenesis Xiaoxuan Fan, Affiliated Hospital of Shaanxi University of Chinese Medicine Title: Kidney-tonifying Chinese medicine can promote the repair of nerve demyelination:An experimental study in demyelinating mouse model Yuning Feng, Affiliated Hospital of Shaanxi University of Chinese Medicine Title: Analysis of risk factors related to Intracerebral Hemorrhage Chong Gao, Hangzhou City University Title: Developing ALS model with neuromuscular organoids Haijun Han, Hangzhou City University Title: Study on FZD6 in depression through hippocampal neurogenesis mediated by Wnt/beta-catenin pathway Xiaohua Jiang, The Chinese University of Hong Kong Title: Application of Ectodermal Mesenchymal Stem Cells in Ischemic Brain Damage Zhanfeng Jiang, General Hospital of Ningxia Medical University Title: Lycium Barbarum Glycopeptide inhibits neuroinflammation by promoting the secretion of DHA by microglia Longjie Lin, Affiliated Hospital of Shaanxi University of Chinese Medicine Title: Research progress on the mechanism of Chinese herbal medicine promoting myelin sheath repair Chang Liu, Shanghai Jiao Tong University Title: Stroke-induced Phenotype of Neuroinflammatory Astrocytes Disrupts Blood-Brain Barrier Integrity via Matrix Metalloproteinase-3 Jingjing Liu, Lanzhou University Title: Fecal microbiome transplantation alleviates manganese-induced neurotoxicity through altering gut microbiota composition and function associated with the cGAS–STING/NLRP3 pathway Sheng Liu, Zhongshan Ophthalmic Center, Sun Yat-Sen University Title: The cellular and molecular mechanisms of visual information processing Yi Wang, Zhejiang Chinese Medical University Title: Adult-born neurons aggravate epileptic seizures via local aberrant excitatory circuits Anguo Wu, Southwest Medical University Title: Targeting autophagy as a therapeutic strategy for the identification of lignans from Peristrophe japonica in Parkinson’s disease Tongtong Xu, Shanghai Jiao Tong University Title: Astrocytic MEGF10- and MERTK-mediated myelin phagocytosis differentially affects white matter repair in mice after chronic cerebral hypoperfusion Qing Zeng, Zhujiang Hospital of Southern Medical University Title: Supramolecular hybrid hydrogel delivers exosomes derived from IL-1β stimulated BMSCs to attenuate neuroinflammation in cerebral ischemia-reperfusion injury 08:30-12:00 Youth Scientists Forum 03 (English) Order of Presentations: Arranged in alphabetical order by their last name Session Chair: Mengliang Zhang (University of Southern Denmark, Denmark) Referees: Wedong Le, John Mitrofanis, Yi Ren, Yang Xiang, Chun-Li Zhang, Mengliang Zhang Junhao Deng, Chinese PLA General Hospital Title: Repopulated microglia promotes tissue repair and functional recovery after spinal cord injury Yuzhen Dong, The First Affiliated Hospital of Xinxiang Medical University Title: The study of regenerative for spinal cord injury (SCI) Lanya Fu, Southern Medical University Title: miR301a knockout attenuates the Wallerian degeneration and peripheral nerve regeneratin via YY1/CXCR4 patway Fanqi Meng, Xuanwu Hospital Capital Medical University Title: Botao Tan, The Second Affiliated Hospital of Chongqing Medical University Title: Activity dependent repair after spinal cord injury Zhifang Xu, Tianjin University of Traditional Chinese Medicine Title: The Mechanism of Wake-Promoting Efficacy of Acupuncture at Jing-Well Points for Traumatic Brain Injury-induced Coma via Regulation of vPAG-Lateral Hypothalamic Circuit Qi Zhan, Tianjin Medical University General Hospital Title: Natural and bioinspired platform for efficient delivery of RNA therapeutics to the central nervous system Deteng Zhang, Qingdao University Title: Bioactive scaffolds enhanced nerve regeneration Lijian Zhang, Affiliated Hospital of Hebei University Title: Molecular mechanism of olfactoryensheathing cells regulating neuroinflammation after spinal cord injury Meng Zhang, Peking University People's Hospital Title: NGF-loaded bionic adhesive chitosan conduit for sutureless repair of peripheral nerve injury Yikui Zhang, Eye Hospital of Wenzhou Medical University Title: Investigating white matter protection strategies via spatial-seq in a large animal model of optic nerve concussion Meidan Zhao, Tianjin University of Traditional Chinese Medicine Title: Adiponectin-mediated electroacupuncture improves depression-like behavior in CUMS rats Meiling Zhou, Jianghan University Title: Ngn2 and Isl1-mediated astrocyte-to-neuron conversion in vivo promotes functional recovery after spinal cord injury Mi Zhou, Tianjin Medical University General Hospital Title: Contact Separation Triboelectric Nanogenerator Based neurostimulation for Effective Sciatic Nerve Restoration Tian Zhou, Chinese Academy of Sciences Title: Blood-brain barrier constituents: emerging phagocytic cells in central nervous system |