Yuanquan Song

Yuanquan Song, PhD

Associate Professor

Raymond G. Perelman Center for Cellular and Molecular Therapeutics

The Children's Hospital of Philadelphia;

Department of Pathology and Laboratory Medicine

University of Pennsylvania, USA

About the Speaker:

Education

B.S. (Biotechnology), Shanghai Jiao Tong University, Shanghai, China, 2002

Ph.D. (Neuroscience), Perelman School of Medicine at the University of Pennsylvania, 2009

Specialty Certification

Postgraduate Training

Postdoctoral Fellow, Physiology, University of California, SanFrancisco; Howard Hughes Medical Institute, 2009-2016

Trainee, Spinal Cord Injury Research Training Program (SCITP) - 2 week course, Ohio State University, Department of Neuroscience, Ohio State University, Columbus, OH, 2015-2015

Awards and Honors

University's Third Class Scholarship, Shanghai Jiao Tong University, 2000

University's Second Class Scholarship, Shanghai Jiao Tong University, 2001

Fine Science Tools Travel Award, University of Pennsylvania, 2005

Neuroscience Imaging Competition, Mahoney Institute of Neurological Sciences Retreat, University of Pennsylvania, 2008

Roman Reed Spinal Cord Injury Research Fund of California, 2012-2012

NIH/NINDS PA-11-197 NIH Pathway to Independence award (K99-R00), 2014-2019

IDDRC New Program Development Award/IDDRC at CHOP and Penn, 2016-2018

Roberts Functional Genomics Rapid Grant/CHOP, 2017-2018

CHOP Pilot grant, 2017-2018

Wings for Life - Spinal Cord Research Foundation, 2018-2020

Roberts Collaborative Forefront Grant/CHOP, 2018-2019

Craig H. Neilsen Foundation, 2019-2021

Roberts Functional Genomics Rapid Grant/CHOP, 2019-2019

The Foerderer award/CHOP, 2020-2021

Sigma Xi, 2020-Present

Memberships and Professional Organizations

Society for Neuroscience, 2009 - Present

Sigma Xi, 2020 - Present

Reviewer, The Health Research Council of New Zealand (HRC), Sir Charles Hercus Research Fellowship, 2020 - 2020

Reviewer, NIH study section (NDPR) Ad Hoc, 2021 - 2021

Reviewer, The Human Frontier Science Program (HFSP) postdoctoral fellowship, 2022 - 2022

Reviewer, NIH study section (CMBG) Ad Hoc, 2023 - 2023

Research Interests:

The long-term goal of the Song lab is to elucidate the cellular and molecular basis governing the formation, maintenance and function of neural circuits under physiological and pathological conditions, using both Drosophila and mammalian models.

With a background in neural development, neural circuits and behavior, fly and mouse genetics, injury and neurodegeneration models, our lab offers a unique skillset and perspective for addressing physiological questions in developmental/functional neurobiology and neurological diseases.

Selected Recent Publications:

1. Li D, Wang Q, Bayat A, Battig MR, Zhou YJ, Bosch DG, van Haaften G, Granger L, Petersen AK, Pérez-Jurado LA, Aznar-Laín G, Aneja A, Hancarova M, Bendova S, Schwarz M, Pourova RK, Sedlacek Z, Keena BA, March ME, Hou CP et al. (2024) Spliceosome malfunction causes neurodevelopmental disorders with overlapping features. J Clin Invest 134:e171235.

2. Rashid A, Wang Q, Song YQ (2023) All hands on deck: Adipocytes lept-in to drive nerve regeneration. Cell Metab 35:2095-2096.

3. Trombley S, Powell J, Guttipatti P, Matamoros A, Lin XH, O'Harrow T, Steinschaden T, Miles L, Wang Q, Wang SC, Qiu JY, Li QY, Li F, Song YQ (2023) Glia instruct axon regeneration via a ternary modulation of neuronal calcium channels in Drosophila. Nat Commun 14:6490.

4. Dong WF, Fekete A, Chen XD, Liu HW, Beilhartz GL, Chen X, Bahrampour S, Xiong Y, Yang Q, Zhao   HY, Kong T, Morioka MS, Jung G, Kim JE, Schramek D, Dirks PB, Song YQ, Kim TH, He Y, Wanggou SY et al. (2023) A designer peptide against the EAG2-Kvβ2 potassium channel targets the interaction of cancer cells and neurons to treat glioblastoma. Nat Cancer 4:1418-1436.