Shunsuke Koga

Shunsuke Koga, MD, PhD

Neuropathology Fellow

Department of Pathology and Laboratory Medicine

Hospital of the University of Pennsylvania, USA

About the Speaker:

Education history:

July 2025 – Present

Fellow

Department of Pathology and Laboratory Medicine

Hospital of the University of Pennsylvania, USA

July 2023 – June 2025

Resident

Department of Pathology and Laboratory Medicine

Hospital of the University of Pennsylvania, USA

December 2020 – June 2023

Assistant Professor

Mayo Clinic Florida, USA

Apr 2014 – December 2020

Post-Doctorate

Mayo Clinic Florida, USA

Research Interest:

The research of Shunsuke Koga, is focused on understanding the clinicopathological correlations of tauopathies and α-synucleinopathies, with a particular focus on progressive supranuclear palsy (PSP), corticobasal degeneration (CBD) and multiple system atrophy (MSA). Specifically, Dr. Koga investigates how comorbid pathologies, such as TDP-43 and Alzheimer's-type pathology, modify clinical presentations of patients with PSP, CBD and MSA.

Selected Recent Publications:

1. Ono D, Dickson DW, Koga S. (2024) Evaluating the efficacy of few-shot learning for GPT-4Vision in neurodegenerative disease histopathology: A comparative analysis with convolutional neural network model. Neuropathol Appl Neurobiol 50:e12997.

2. Kim M, Sekiya H, Yao G, et al. (2023) Diagnosis of Alzheimer Disease and Tauopathies on Whole-Slide Histopathology Images Using a Weakly Supervised Deep Learning Algorithm. Lab Invest 103:100127.

3. Koga S, Josephs KA, Aiba I, Yoshida M, Dickson DW (2022) Neuropathology and emerging biomarkers in corticobasal syndrome. J Neurol Neurosurg Psychiatry 93:919-929. Online ahead of print.

4. Koga S, Ikeda A, Dickson DW (2022) Deep learning-based model for diagnosing Alzheimer's disease and tauopathies. Neuropathol Appl Neurobiol 48:e12759

5. Koga S, Sekiya H, Kondru N, Ross OA, Dickson DW (2021) Neuropathology and molecular diagnosis of Synucleinopathies. Mol Neurodegener 16:83.

6. Koga S, Dickson DW, Wszolek ZK (2021) Neuropathology of progressive supranuclear palsy after treatment with tilavonemab. Lancet Neurol 20:786-787.