Dirk M. Hermann

Dirk M. Hermann, Prof. Dr.

Vascular Neurology, Dementia and Age Research

Clinic for Neurology

University Hospital Essen, Germany

About the Speaker:

Prof. Dirk M. Hermann obtained his MD from Justus Liebig University Gießen, Germany in 1995. After postdoctoral studies at the Max Planck Institute of Psychiatry in Munich and Max Planck Institute for Neurological Research in Cologne, he performed his clinical training at the Department of Neurology at Eberhard Karls University in Tübingen, before becoming associate professor and consultant at the Department of Neurology at the University Hospital Zurich, Switzerland. Currently, he is Professor of Vascular Neurology, Dementia and Ageing Research at the University Hospital Essen, Germany. His research centers on the promotion of tissue remodeling and neuroplasticity in the ischemic brain. Prof. Dirk M. Hermann has made seminal contributions on strategies that enhance neurological recovery and neuronal rewiring in the stroke recovery phase.

Selected Recent Publications:

1. Wei W, Lattau SSJ, Xin W, Pan Y, Tatenhorst L, Zhang L, Graf I, Kuang Y, Zheng X, Hao Z, Popa-Wagner A, Gerner ST, Huber S, Nietert M, Klose C, Kilic E, Hermann DM, Bähr M, Huttner HB, Liu H et al. (2024) Dynamic Brain Lipid Profiles Modulate Microglial Lipid Droplet Accumulation and Inflammation Under Ischemic Conditions in Mice. Adv Sci (Weinh) 11:e2306863.

2. Kronimus Y, Albus A, Hasenberg M, Walkenfort B, Seifert M, Budeus B, Gronewold J, Hermann DM, Ross JA, Lochnit G, Galuska SP, Marcus K, Sitek B, Klotsche J, Mengel D, Neumann S, Dodel R (2023) Fc N-glycosylation of autoreactive Aβ antibodies as a blood-based biomarker for Alzheimer's disease. Alzheimers Dement 19:5563-5572.

3. Xin W, Pan Y, Wei W, Tatenhorst L, Graf I, Popa-Wagner A, Gerner ST, Huber S, Kilic E, Hermann DM, Bähr M, Huttner HB, Doeppner TR (2023) Preconditioned extracellular vesicles from hypoxic microglia reduce poststroke AQP4 depolarization, disturbed cerebrospinal fluid flow, astrogliosis, and neuroinflammation. Theranostics 13:4197-4216.

4. Rohlfing AK, Kolb K, Sigle M, Ziegler M, Bild A, Münzer P, Sudmann J, Dicenta V, Harm T, Manke MC, Geue S, Kremser M, Chatterjee M, Liang C, von Eysmondt H, Dandekar T, Heinzmann D, Günter M, von Ungern-Sternberg S, Büttcher M et al. (2022) ACKR3 regulates platelet activation and ischemia-reperfusion tissue injury. Nat Commun 13:1823.

5. Beuker C, Schafflick D, Strecker JK, Heming M, Li X, Wolbert J, Schmidt-Pogoda A, Thomas C, Kuhlmann T, Aranda-Pardos I, A-Gonzalez N, Kumar PA, Werner Y, Kilic E, Hermann DM, Wiendl H, Stumm R, Meyer Zu Hörste G, Minnerup J (2022) Stroke induces disease-specific myeloid cells in the brain parenchyma and pia. Nat Commun 13:945.