Pu Chun Ke

Pu Chun Ke, PhD.

Professor (Research)

Drug Delivery, Disposition and Dynamics

Monash Institute of Pharmaceutical Sciences

Monash University, Australia

2025 UM Distinguished Visiting Scholar

University of Macau, China

About the Speaker:

Pu Chun Ke is a Professor (Research) at Monash Institute of Pharmaceutical Sciences, Monash University in Melbourne, Australia. Prof Ke was a recipient of the Inaugural Supervision Excellence Award (2019) from the ARC Center of Excellence at Monash Institute of Pharmaceutical Sciences in Australia, a Faculty Achievement in the Sciences Award (2012) from Clemson University, a CAREER Award (2008) from the National Science Foundation and an LJIS Postdoctoral Fellowship in Biophysics (2001-2003) from the University of California, San Diego in the United States. He has authored 175 peer-reviewed journal papers (15 featured as journal covers) on amyloidogenesis in Alzheimer's, Parkinson's and type 2 diabetes, nanomedicine, and environmental science. His research career has spanned over three continents funded by NSF and EPA in the United States, by CSIRO and CBNS in Australia, and by NSFC and MOST in China. He has served on US, European and Australia federal grant panels, and as a frequent referee for 99 major journals. He is on the editorial boards of Biophysical Chemistry (Elsevier) and ACS Nanoscience Au.

Specification

amyloid protein aggregation, nanomedicine, biophysics, environmental science nano

Selected Recent Publications:

1. Tang H, Andrikopoulos N, Li Y, Ke S, Sun Y, Ding F, Ke PC (2025) Emerging biophysical origins and pathogenic implications of amyloid oligomers. Nat Commun 16:2937.

2. Liang X, Huang G, Wang Y, Andrikopoulos N, Tang H, Ding F, Li Y, Ke PC (2025) Polystyrene Nanoplastics Hitch-Hike the Gut-Brain Axis to Exacerbate Parkinson's Pathology. ACS Nano 19:5475-5492.

3. Li Y, Ni N, Lee M, Wei W, Andrikopoulos N, Kakinen A, Davis TP, Song Y, Ding F, Leong DT, Ke PC (2024) Endothelial leakiness elicited by amyloid protein aggregation. Nat Commun 15:613.

4. Andrikopoulos N, Tang H, Wang Y, Liang X, Li Y, Davis TP, Ke PC (2024) Exploring Peptido-Nanocomposites in the Context of Amyloid Diseases. Angew Chem Int Ed Engl 63:e202309958.

5. Setyawati MI, Wang Q, Ni N, Tee JK, Ariga K, Ke PC, Ho HK, Wang Y, Leong DT (2023) Engineering tumoral vascular leakiness with gold nanoparticles. Nat Commun 14:4269.