Manuel Menendez-Gonzalez

Manuel Menendez-Gonzalez

Professor

Departamento de Medicina, Universidad de Oviedo, Spain;

Servicio de Neurología, Hospital Universitario Central de Asturias, Spain;

Grupo de Investigación Básica-Clínica en Neurología

Instituto de Investigación Sanitaria del Principado de Asturias, Spain

About the Speaker:

Prof. Manuel Menéndez-González is a tenured professor at the University of Oviedo, and a neurologist at the Hospital Universitario Central de Asturias. After completing his neurology residency, he received specialized training in dementias and behavioral neurology and has participated in numerous courses, conferences, and symposia. He belongs to various scientific societies and professional associations and has held various management and participation roles in institutions, commissions, committees, and societies. He has a solid academic background with several postgraduate diplomas. His teaching experience includes neuroanatomy and clinical neurology courses, particularly on neurodegenerative diseases, and he has supervised master's and doctoral theses.

As a researcher, Menéndez-González has participated in research projects funded by public and private funds, health outcomes research studies, and clinical trials. His expertise spans from basic and applied research to transferring results into clinical practice, highlighting his commitment to innovation and improving treatments for neurological diseases. He has served as the Principal Investigator (PI) for projects funded at regional, national, and European levels. He has published extensively in books, journals, and conference proceedings (+200 papers, H-index: 38). He is recognized for his work in the genetics of neurodegenerative diseases and in developing innovative technologies for intrathecal drug delivery for these conditions.

Selected Recent Publications:

1. Menendez-Gonzalez M (2025) Implementing a tridimensional diagnostic framework for personalized medicine in neurodegenerative diseases. Alzheimers Dement 21:e14591.

2. Bellenguez C, Küçükali F, Jansen IE, Kleineidam L, Moreno-Grau S, Amin N, Naj AC, Campos-Martin R, Grenier-Boley B, Andrade V, Holmans PA, Boland A, Damotte V, van der Lee SJ, Costa MR, Kuulasmaa T, Yang Q, de Rojas I, Bis JC, Yaqub A, et al. (2022) New insights into the genetic etiology of Alzheimer's disease and related dementias. Nat Genet 54:412-436.

3. de Rojas I, Moreno-Grau S, Tesi N, Grenier-Boley B, Andrade V, Jansen IE, Pedersen NL, Stringa N, Zettergren A, Hernández I, Montrreal L, Antúnez C, Antonell A, Tankard RM, Bis JC, Sims R, Bellenguez C, Quintela I, González-Perez A, Calero M,   et al. (2021) Common variants in Alzheimer's disease and risk stratification by polygenic risk scores. Nat Commun 12:3417.

4. Blauwendraat C, Iwaki H, Makarious MB, Bandres-Ciga S, Leonard HL, Grenn FP, Lake J, Krohn L, Tan M, Kim JJ, Gibbs JR, Hernandez DG, Ruskey JA, Pihlstrøm L, Toft M, van Hilten JJ, Marinus J, Schulte C, Brockmann K, Sharma M, et al. (2021) Investigation of Autosomal Genetic Sex Differences in Parkinson's Disease. Ann Neurol 90):35-42.

5. Kia DA, Zhang D, Guelfi S, Manzoni C, Hubbard L, Reynolds RH, Botía J, Ryten M, Ferrari R, Lewis PA, Williams N, Trabzuni D, Hardy J, Wood NW; United Kingdom Brain Expression Consortium (UKBEC) and the International Parkinson’s Disease Genomics Consortium (IPDGC) (2021) Identification of Candidate Parkinson Disease Genes by Integrating Genome-Wide Association Study, Expression, and Epigenetic Data Sets. JAMA Neurol 78:464-472.